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2008 1
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Page 1
The Structural Basis of Necroptotic Cell Death Signaling.
Petrie EJ, Czabotar PE, Murphy JM. Petrie EJ, et al. Trends Biochem Sci. 2019 Jan;44(1):53-63. doi: 10.1016/j.tibs.2018.11.002. Epub 2018 Nov 30. Trends Biochem Sci. 2019. PMID: 30509860 Review.
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues.
Davies KA, Fitzgibbon C, Young SN, Garnish SE, Yeung W, Coursier D, Birkinshaw RW, Sandow JJ, Lehmann WIL, Liang LY, Lucet IS, Chalmers JD, Patrick WM, Kannan N, Petrie EJ, Czabotar PE, Murphy JM. Davies KA, et al. Among authors: petrie ej. Nat Commun. 2020 Jun 19;11(1):3060. doi: 10.1038/s41467-020-16823-3. Nat Commun. 2020. PMID: 32561735 Free PMC article.
Conformational interconversion of MLKL and disengagement from RIPK3 precede cell death by necroptosis.
Garnish SE, Meng Y, Koide A, Sandow JJ, Denbaum E, Jacobsen AV, Yeung W, Samson AL, Horne CR, Fitzgibbon C, Young SN, Smith PPC, Webb AI, Petrie EJ, Hildebrand JM, Kannan N, Czabotar PE, Koide S, Murphy JM. Garnish SE, et al. Among authors: petrie ej. Nat Commun. 2021 Apr 13;12(1):2211. doi: 10.1038/s41467-021-22400-z. Nat Commun. 2021. PMID: 33850121 Free PMC article.
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.
Petrie EJ, Sandow JJ, Lehmann WIL, Liang LY, Coursier D, Young SN, Kersten WJA, Fitzgibbon C, Samson AL, Jacobsen AV, Lowes KN, Au AE, Jousset Sabroux H, Lalaoui N, Webb AI, Lessene G, Manning G, Lucet IS, Murphy JM. Petrie EJ, et al. Cell Rep. 2019 Sep 24;28(13):3309-3319.e5. doi: 10.1016/j.celrep.2019.08.055. Cell Rep. 2019. PMID: 31553902 Free article.
MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis.
Samson AL, Zhang Y, Geoghegan ND, Gavin XJ, Davies KA, Mlodzianoski MJ, Whitehead LW, Frank D, Garnish SE, Fitzgibbon C, Hempel A, Young SN, Jacobsen AV, Cawthorne W, Petrie EJ, Faux MC, Shield-Artin K, Lalaoui N, Hildebrand JM, Silke J, Rogers KL, Lessene G, Hawkins ED, Murphy JM. Samson AL, et al. Among authors: petrie ej. Nat Commun. 2020 Jun 19;11(1):3151. doi: 10.1038/s41467-020-16887-1. Nat Commun. 2020. PMID: 32561730 Free PMC article.
Membrane permeabilization is mediated by distinct epitopes in mouse and human orthologs of the necroptosis effector, MLKL.
Sethi A, Horne CR, Fitzgibbon C, Wilde K, Davies KA, Garnish SE, Jacobsen AV, Samson AL, Hildebrand JM, Wardak A, Czabotar PE, Petrie EJ, Gooley PR, Murphy JM. Sethi A, et al. Among authors: petrie ej. Cell Death Differ. 2022 Sep;29(9):1804-1815. doi: 10.1038/s41418-022-00965-6. Epub 2022 Mar 9. Cell Death Differ. 2022. PMID: 35264780 Free PMC article.
Identification of MLKL membrane translocation as a checkpoint in necroptotic cell death using Monobodies.
Petrie EJ, Birkinshaw RW, Koide A, Denbaum E, Hildebrand JM, Garnish SE, Davies KA, Sandow JJ, Samson AL, Gavin X, Fitzgibbon C, Young SN, Hennessy PJ, Smith PPC, Webb AI, Czabotar PE, Koide S, Murphy JM. Petrie EJ, et al. Proc Natl Acad Sci U S A. 2020 Apr 14;117(15):8468-8475. doi: 10.1073/pnas.1919960117. Epub 2020 Mar 31. Proc Natl Acad Sci U S A. 2020. PMID: 32234780 Free PMC article.
29 results